CoQ10 for Fertility and Reproductive Health

CoQ10 ‚Äď A Powerful Antioxidant for Fertility

Coenzyme Q10 (CoQ10) is a natural substance produced by the body. First identified in the 1950s, CoQ10 is a powerful antioxidant ‚Äď a nutrient shown to defend against cellular damage caused by harmful molecules called free radicals. While necessary for certain reproductive processes, like ovulation, excess free radicals can lead to oxidative stress, which can damage eggs and sperm cells and impair their functioning. However, taking antioxidant supplements, like CoQ10, may reduce oxidative stress and any resulting inflammation. CoQ10 may also improve egg and sperm quality, as well as pregnancy rates. A fat-soluble nutrient, CoQ10 should be taken with a meal containing fat or oil for better absorption.

CoQ10 Benefits for All

While found throughout the body, the highest levels of CoQ10 are found in organs with high rates of metabolism, like the heart, kidney, and liver. It‚Äôs also concentrated in the mitochondria ‚Äď also known as the ‚Äúpowerhouse of the cell‚ÄĚ ‚Äď which is an organelle responsible for cellular energy production. CoQ10 is essential, as it converts fats and carbohydrates into adenosine triphosphate (ATP), an organic compound that provides readily releasable energy and contributes to crucial cellular functions, like DNA/RNA formation and muscle contraction.¬†

CoQ10 for Female Fertility

With its energy production properties, CoQ10 is a valuable nutrient for women’s fertility. Both eggs and sperm require very high levels of cellular energy, meaning more CoQ10 is needed. For eggs, this additional energy is used for cell division during early embryo development. Lower CoQ10 levels reduce eggs’ energy production, impacting their quality and making them less viable for conception. After fertilization, this mitochondrial energy is vital, as the embryo requires it for healthy development. 

As women age, their eggs are more likely to have chromosomal errors, leading to an increased risk of miscarriage or having a child with a genetic condition, such as Down syndrome. As an antioxidant, CoQ10 reduces oxidative stress associated with diminished ovarian reserve (i.e., poor egg quality or low egg count). CoQ10 may promote a higher fertilization rate and more high-quality embryos. It may also boost the number of ovarian follicles and improve ovulation. 

CoQ10 for Male Fertility

As with egg quality, CoQ10 deficiencies are associated with lower sperm energy production, which affects their quality and ability to reach or penetrate an egg. Indeed, CoQ10 supplementation, whether alone or with other antioxidants, may promote overall sperm health and quality, which is the most common cause of male fertility. Higher CoQ10 levels are associated with increased motility, concentration, and sperm count, thereby increasing men’s chances of successful egg fertilization.

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Your Questions, Answered:‚Ä® CoQ10 Fertility FAQ

  • Yes, CoQ10 supplementation can improve conception, as it has been shown to support egg and sperm quality, as well as pregnancy rates. Many fertility experts consider this nutrient to be an important component of any fertility treatment plan.¬†

    For couples considering assisted reproductive technology (ART), CoQ10 may support in vitro fertilization (IVF) treatment, as it may increase pregnancy rates; one study showed that women with higher concentrations in the fluid surrounding their eggs experienced better-quality embryos and higher pregnancy rates.

    Taking daily multivitamins and for women, prenatal vitamins, may also benefit fertility health. Additionally, NutraBloom offers multiple products rich in antioxidants, nutrients found to defend against cellular damage caused by harmful molecules, called free radicals. While necessary for certain processes, like ovulation, excess free radicals can lead to oxidative stress, which can damage cell health and function. Antioxidants may support female and male fertility, including improving egg and sperm quality and pregnancy rates. 

  • Before trying to become pregnant naturally, it is typically recommended that CoQ10 supplements be taken for at least 90 days. For women undergoing IVF, it‚Äôs generally recommended to start taking CoQ10 supplements about three months before they start treatment.

    These nutrients may also support male fertility, including sperm health and hormone production. Additionally, men may opt to take daily supplements of vitamin D, the mineral zinc, and such antioxidants as lycopene and grape seed extract. There are also nutrients, like the antioxidants vitamins C and E, that often work closely together to promote fertility. For women, these benefits may include those for ovulation, fertilization and egg health, and such conditions as endometriosis. They may also benefit male fertility, specifically sperm health and function.  

  • CoQ10 supplementation has been found to increase the number of ovarian follicles, which are small fluid sacs that hold eggs. Studies show that this nutrient significantly reduces oxidative stress levels in follicles, especially among women under 35 years old.

  • If you‚Äôre taking CoQ10 for sperm health, it‚Äôs not clear how long it will take until you notice improvements. However, after puberty, new sperm cells are produced continuously, and on average, they take about two and a half months to fully develop. One study from 2004 showed that taking CoQ10 for six months improved semen parameters.

  • With reduced levels of CoQ10, sperm receive less cellular energy, impacting their quality and making them less viable for conception. However, various studies show that CoQ10, whether taken alone or with other antioxidants, may support sperm health and quality. Increased CoQ10 levels are associated with improved motility, concentration, and sperm count, all of which contribute to the likelihood of fertilizing an egg.¬†

  • Should you be dealing with infertility, you may not be sure when to schedule an appointment with a fertility specialist, if at all. These physicians receive special training in treating men and women with conception issues, and typically, they‚Äôre board-certified in both obstetrics and gynecology, and possibly, reproductive endocrinology and infertility. When deciding whether to see a fertility specialist, certain factors, such as your age, or having existing conditions, like thyroid disease or PCOS, may factor into your decision. It‚Äôs recommended that women first talk with their gynecologist or primary care physician if they are either:

    • Under age 35, and have not conceived after a year of unprotected sex.
    • Are 35 years or older, and have not conceived after six months of unprotected sex.

    If you’re ready to connect with a specialist, request a consultation with our trusted network today.